References and research

Our registered claim that Regulin increases lambing by 20% is based on the following research

Animal Reproduction Science, 30 (1992) 225-258 225; Elsevier Science Publishers B.V., Amsterdam
Optimum use of subcutaneous melatonin implants to enhance the reproductive performance of seasonal and non-seasonal sheep joined in spring and early summer A.H. Williams a, S.R. McPhee b, J.L. Reeve c and L.D. Staples b

a Victorian Institute of Animal Science, Werribee, Vic. 3030, Australia |  b Applied Biotechnologies Pry Ltd, PO Box 59, East Kew, Vic. 3102, Australia | c Rutherglen Research Institute, Department of Agriculture, Rutherglen, Vic. 3685, Australia

Download other research papers on the effects of melatonin on reproduction


Abecia 2012 Hormonal control of reproduction in small ruminants
Abecia, Pharmaceutical control of reproduction in Sheep and Goats
Bramis, Effects of melatonin on dairy sheep and goats
Yildiz, 2015, Improving the conception rate of dairy cows by using a melatonin implant

Sheep (Ewes)

Abbas, et. al. 2004 Improvement in reproductive performance
Abecia 2012 Hormonal control of reproduction in small ruminants
Abecia, et. al. 2014 Effect of melatonin and the presence of peers
Abecia, et. al. 2004 Effect melatonin on wool growth and thyroxine secretion
Abecia, et. al. 2005 Effect of melatonin on milk production
Abecia, et. al. 2005 Effect of melatonin on ovarian response
Abecia, et. al. 2006 Effect of melatonin on reproductive performance
Abecia, et. al. 2007 Effect of melatonin on wool quality
Abecia, et. al. 2008 Effect of melatonin on ovary, embryo and pregnancy
Abecia, et. al. 2009 Effect of melatonin and undernutrition on viability of ovine embryos
Abecia, Pharmaceutical control of reproduction in Sheep and Goats
Arrebola, et. al. 2009 Rainfall and lamb production in Merinos after treatment with melatonin
Bonev 2012 Effect of melatonin on fertility fecundity litter size
Bouroutzika, Kouretas, et. al. 2020 Administration of melatonin to pregnant ewes under heat-stress conditions
Bramis, Effects of melatonin on dairy sheep and goats
Buffoni, et. al. 2014 The effect of melatonin and season on in vivo embryo
Carcangiu, et. al. 2006 Melatonin shortens puberty in ewe lambs
Carcangiu, et. al. 2008 Melatonin and different Body Condition Scores
Carcangiu, et. al. 2010 Melatonin and AI
Carcangiu, et. al. 2010 Melatonin improves reproductive efficiency
Carcangiu, et. al. 2012 Melatonin first and subsequent lambings
Casao, et. al. The effects of melatonin on in vitro oocyte competence
Correia, et. al. Churra Galega Braganca ewes
Forcada, et. al. 2006 The effect of melatonin after super-ovulation
Gomez-Brunet, et. al. 1995 Reproductive response and LH secretion in ewes
Gutierrez, et. al. Production of Christmas lambs
Haresign, 1992, The effect of melatonin in low land ewes
Luridiana, et. al. 2015 Reproductive recovery in sheep with difference BCS and age
Luther, Follicular Development and Oocyte Quality in the Anestrous Ewes
Luther, Production of Embryos in Seasonally Anestrous Ewes
Martin, et. al 2003 Melatonin treatments or vaginal sponges
Mura, et. al. 2010 Carry-over effect in reproduction
Mura, et. al. 2010 Use of melatonin to bring mating forward
Mura, et. al. 2017 Melatonin treatment in winter and spring and reproductive recovery
Palacin, et. al 2010 Meta analysis melatonin improves reproductive performance
Scott, et. al. 2008 Melatonin increases fetal numbers
Staples, et. al. 1988 Border Leicester X Merino ewes
Uslu, et. al. 2012 Effects of oestrus synchronisation using melatonin and norgestomet
Vacca, et. al. 2007 Melatonin in Sarda sheep
Vasquez, et. al. 2009 Melatonin can affect embryo development in vitro
Vasquez, et. al. 2013 Effect of exogenous melatonin on embryo viability
Watts, 2016, Building flock environmental fitness
Williams, et. al. 1992 Optimum use of subcutaneous melatonin.pdf


Abecia, et. al. 2009 Melatonin impact on rams
Abecia, et. al. 2017 Extended day length performance in rams
Abecia, et. al. Treated rams increase pregnancy rates
ACP in RAMS Vet Bulletin
Size: 858KB
Arranz, et. al. 1995 Sperm production in rams
Beliers, Exogenic melatonin in Rembi and Hamra rams
Casao, et. al 2010 Melatonin effects on ram sperm and fertility rates
Casao, et. al. 2012 Melatonin receptors in ram spermatazoa
deGraaf, et. al. Melatonin in rams advances breeding season and increases testicular function
Size: 1MB
Published: 17 June 2020
Kleeman, et. al. 2014 Reproductive Performance of Young BL Rams X Merino Ewes
Lincoln, et. al. 1999 Prolactin Replacement Fails to Inhibit Reactivation of Gonadotropin Secretion in Rams
Rekik, et. al. 2015 Melatonin enhances the reproductive capacity of young rams
Rosa, et. al. 2000 Rams and plasma testosterone concentration, sexual behaviour


Abecia 2012 Hormonal control of reproduction in small ruminants
Abecia, Pharmaceutical control of reproduction in Sheep and Goats
Bramis, Effects of melatonin on dairy sheep and goats
Chemineau, 1996 Mastering the seasonal reproduction in sheep and goats
Corujeira, et. al. 2012 Portuguese serrana goats
Duan, et. al. 2015 Effects of melatonin implantation on cashmere goats, fibre yield and characteristics
duPreez, 2001 Out of season breeding in milk goats
Lemeiter, 2004, Use of Melatonin in Caprin Goats
Zaragaza, Effect of melatonin implants in goat females
Zaragaza, Melatonin improves seasonal anoestrus in goats
Zarazaga, 2011 Long days and melatonin in Mediterranean goats
Zarazaga, 2011 Long days in female goats
Zarazaga, 2017 Effect on female goats with decreasing BCS


Fisher, et. al. 1988 Effects of melatonin on seasonal physiology of red deer 1988.pdf,
Fisher, et. al. Manipulating breeding in red and fallow deer